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PD-1 binds to PD-L2

Information illustration
Free illustration of the binding of the surface protein PD-L2 to PD-1 as a surface model with indicated ribbon model on a white background. Programmed cell death 1 ligand 2 is involved in the negative regulation of the adaptive immune response together with the receptor PD-1. PD-1 (red) is found on the surface of T cells and interacts with the ligand protein PD-L2 which is found on the surface of regulatory cells, such as the cells that present antigens from invaders.
Illustration based on structural data from Yan, Q., Lazar-Molnar, E., Cao, E., Ramagopal, U.A., Toro, R., Nathenson, S.G., Almo, S.C.Purchase an extended license of this illustration in high resolution:
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