Graphic showing the causes and effects of a gene defect in multidrug resistance protein-1 in some dog breeds.

The MDR1 gene defect occurs mainly in the Collie or related breeds. As a result, the P-glycoprotein is either insufficiently produced or not produced at all, which has significant effects on the function of the blood-brain barrier, kidney, intestine, liver and hematopoiesis in the bone marrow. The cause lies in the absence of a few base pairs of the dog's DNA.

 

Project details: 

Content: Graphic - German and English

Utilization: publication, website, print, poster print

Specifications: DIN A2 - 300 dpi (4961 x 7016 Pixel)

Client: TransMIT GmbH - Prof. Dr. Joachim Geyer

The rights of use for the illustrations shown here lie with the client; use is not permitted. The images are protected with watermarks Realization by Yvonne Grabowski - Grafikwerkstatt Wuppertal.

 

 

 

 

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