Illustrations CLL active substance

Illustrations on the mode of action of a BTK inhibitor in CLL (chronic lymphocytic leukemia) on the B cells in the lymph nodes.

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03/13/2019
More about -> Cancer, Illustrations, Oncology, Therapy

In chronic lymphocytic leukemia, the number of B cells is abnormally elevated. The lymph nodes are swollen due to the insertion of B cells. The active substance “Ibrutinib” blocks the interaction of BTK (Brutone Tyrosine Kinase) and transcription factor NFkB in the B cells, which enables cell death and thereby reduces their number. As more and more B-cells and also BTK are produced, a continuous intake of the drug is necessary to reduce the number of B-cells.

Project description:

Content: 5 illustrations

Utilization: printed information folder for sales force

Specifications: Print, DIN A5 / 300dpi

Client: Sir Prise & Lady Buy / Janssen Swiss

The rights of use of the illustrations shown are with the respective clients. The images are protected with a watermark.

CLL wirkstoff b zellen ntk — The drug binds to the BTK and prevents interaction with the transcription factor NFkB

CLL permanente abgabe wirkstoff b zelle — Because BTK is still being re-produced by the B cell, the drug must be taken continuously

skizze cll lymphknoten b zellen — Rough sketch of the images for usage in pre-production

CLL lymph nodes

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