Animation transdermal administration of active substance

Comparison of oral (left) and transdermal (right) uptake of an active substance

September 5, 2018

Oral and transdermal administration are two common methods of delivering active ingredients to the body.

In oral administration, the active ingredient is taken orally, i.e. usually in the form of a pill or capsule, and then absorbed via the gastrointestinal tract. In transdermal administration, the active ingredient is applied to the skin and then absorbed through the skin.

With oral administration, bioavailability may be lower than with transdermal administration because the active ingredient may be metabolized in the liver and digestive tract, reducing the amount of active ingredient that enters the bloodstream. Transdermal administration, on the other hand, may have higher bioavailability because the active ingredient is absorbed directly into the bloodstream without being metabolized in the liver or digestive tract.

Oral administration may have a slower onset of action because the active ingredient must first be absorbed through the digestive tract before it enters the bloodstream. However, the duration of action may be longer because the active ingredient may be released slowly over time. Transdermal administration may have a faster onset of action because the active ingredient is absorbed directly into the bloodstream, but the duration of action may be shorter because the active ingredient is rapidly metabolized and excreted from the body.

Design a comparative animation on the benefits of transdermal administration of an active ingredient compared to oral ingestion. Summary animation on the key features of the active ingredient.