3D Animation Crohn’s disease

3D animation of pathophysiological processes in Crohn's disease. The focus of the 3D animation was on the visualization of the cellular mechanisms of the auto-immune reactions.

Rights of use of the visual material: Client (nda)
Music: Kevin McLeod – As I figure – License: Creative Commons (CC BY 3.0)


Crohn’s disease is a form of inflammatory bowel disease (IBD) that causes inflammation of the digestive tract. It can affect any part of the digestive tract from the mouth to the anus, but most commonly affects the lower part of the small intestine (ileum) and the beginning of the large intestine (colon).

Symptoms of Crohn’s disease include abdominal pain, diarrhea, weight loss, fatigue, and malnutrition. The exact cause of Crohn’s disease is not known, but it is thought to be a combination of genetic and environmental factors. The view that Crohn’s disease is a classic autoimmune disease is now considered outdated.


The focus of the 3D animation was the presentation of the processes in the immune system during a disease with Crohn’s disease. In particular, the function of various interleukins was addressed, which act as endogenous messengers of the cells of the immune system and play an important role in inflammatory processes. Therefore, the influencing of these peptide hormones represents an approach in the therapy of Crohn’s disease.

Project details: 

Content: Crohn’s disease disease – Length 3:00 minutes. Languages: Voiceovers in German + English.

Utilization: Website, Youtube, medical congresses and fairs

Specifications: Full HD – Resolution 1920*1080 pixel

Client: nda

The rights of use of the illustrations shown are with the respective clients.

Screenshots Crohn’s disease:

intestinal wall
Healthy intestinal wall
Morbus Crohn - Intestinal wall
Crohn’s disease – Immune reaction intestinal wall
Illustration of different interleukins
Monoclonal antibodies
Monoclonal antibodies
Dendritic cells  t-helper cells intestinal wall
Dendritic cells and t-helper cells on the intestinal wall